Education
| 2018 | Ph.D. in Medical Science, Oita University, Japan |
| 2013 | M.Sc. in Medical Microbiology, Chulalongkorn University, Thailand |
| 2010 | B.Sc. in Microbiology, Burapha University, Thailand |
Training
| 2020 | Assistant Professor, Department of Microbiology and Immunology, Graduate School of Medicine, Hirosaki University, Japan |
| 2018 | Postdoctoral Fellow, Research Institute for Microbial Diseases (RIMD), Osaka University, Japan |
Research Interest
- Molecular epidemiology and virulence genes of H. pylori
- Antibiotic resistance mechanisms and resistance-associated mutations in H. pylori
- Biomarker discovery for H. pylori-associated gastric cancer
- Microbial interaction in a co-infection system
- Bacterial extracellular vesicles and their roles in pathogenesis and applications
Publications
- From Orcid: https://orcid.org/0000-0002-9961-9350
- From Pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=subsomwong+phawinee
- From Research gate: https://www.researchgate.net/profile/Phawinee-Subsomwong
Selected Publications
1. Nakane A, Subsomwong P, Takahashi T, Ito K, Asano K. Salmon nasal cartilage proteoglycan up-regulates Listeria monocytogenes-mediated immune response in mice. Curr Res Microb Sci. 2025 Aug 27;9:100465. doi: 10.1016/j.crmicr.2025.100465. PMID: 40979681
2.Tomonari K, Saruuljavkhlan B, Alfaray RI, Fauzia KA, Matsunari O, Chinda D, Shimoyama T, Subsomwong P, Kinjo N, Kinjo T, Hanamure Y, Shinzato M, Suzuki R, Kinjo F, Takigami S, Fujioka T, Matsuhisa T, Akada J, Matsumoto T, Yamaoka Y. Fine-scale population structure of Japanese Helicobacter pylori provides new anthropological and epidemiological insights. Microb Genom. 2025 Jun;11(6):001419. doi: 10.1099/mgen.0.001419. PMID: 40493491
3.Subsomwong P, Asano K, Akada J, Matsumoto T, Nakane A, Yamaoka Y. Proteomic profiling of extracellular vesicles reveals potential biomarkers for Helicobacter pylori infection and gastric cancer. Helicobacter. 2025 Mar-Apr;30(2):e70022. doi: 10.1111/hel.70022. PMID: 40033163
4.Watabe N, Subsomwong P, Yamane K, Asano K, Nakane A. Polygonum tinctorium extract suppresses the virulence of methicillin-resistant Staphylococcus aureus by disrupting its extracellular vesicles. J Ethnopharmacol. 2025 Jan 30;337(Pt 3):118933. doi: 10.1016/j.jep.2024.118933. PMID: 39396717.
5. Tourrette E, Torres RC, Svensson SL, Matsumoto T, Miftahussurur M, Fauzia KA, Alfaray RI, Vilaichone RK, Tuan VP; Helicobacter Genomics Consortium; Wang D, Yadegar A, Olsson LM, Zhou Z, Yamaoka Y, Thorell K, Falush D. An ancient ecospecies of Helicobacter pylori. Nature. 2024 Nov;635(8037):178-185. doi: 10.1038/s41586-024-07991-z. PMID: 39415013
6.Subsomwong P, Teng W, Ishiai T, Narita K, Sukchawalit R, Nakane A, Asano K. Extracellular vesicles from Staphylococcus aureus promote the pathogenicity of Pseudomonas aeruginosa. Microbiol Res. 2024 Apr;281:127612. doi: 10.1016/j.micres.2024.127612. PMID: 38244256.
7.Ishiai T, Subsomwong P, Narita K, Kawai N, Teng W, Suzuki S, Sukchawalit R, Nakane A, Asano K. Extracellular vesicles of Pseudomonas aeruginosa downregulate pyruvate fermentation enzymes and inhibit the initial growth of Staphylococcus aureus. Curr Res Microb Sci. 2023 Apr 20;4:100190. doi: 10.1016/j.crmicr.2023.100190. PMID: 37131486
8.Suzuki S, Subsomwong P, Narita K, Kawai N, Ishiai T, Teng W, Sukchawalit R, Nakane A, Tasaka S, Asano K. Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia. PLoS One. 2023 Mar 15;18(3):e0283109. doi: 10.1371/journal.pone.0283109. PMID: 36920961
9.Subsomwong P, Doohan D, Fauzia KA, Akada J, Matsumoto T, Yee TT, Htet K, Waskito LA, Tuan VP, Uchida T, Matsuhisa T, Yamaoka Y. Next-Generation Sequencing-Based Study of Helicobacter pylori Isolates from Myanmar and Their Susceptibility to Antibiotics. Microorganisms. 2022 Jan 17;10(1):196. doi: 10.3390/microorganisms10010196. PMID: 35056645
10.Asano K, Hirose S, Narita K, Subsomwong P, Kawai N, Sukchawalit R, Nakane A. Extracellular vesicles from methicillin resistant Staphylococcus aureus stimulate proinflammatory cytokine production and trigger IgE-mediated hypersensitivity. Emerg Microbes Infect. 2021 Dec;10(1):2000-2009. doi: 10.1080/22221751.2021.1991239. PMID: 34623928
11.Kinoshita-Daitoku R, Kiga K, Miyakoshi M, Otsubo R, Ogura Y, Sanada T, Bo Z, Phuoc TV, Okano T, Iida T, Yokomori R, Kuroda E, Hirukawa S, Tanaka M, Sood A, Subsomwong P, Ashida H, Binh TT, Nguyen LT, Van KV, Ho DQD, Nakai K, Suzuki T, Yamaoka Y, Hayashi T, Mimuro H. A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment. Nat Commun. 2021 Apr 9;12(1):2085. doi: 10.1038/s41467-021-22317-7. PMID: 33837194
12.Subsomwong P, Miftahussurur M, Uchida T, Vilaichone RK, Ratanachu-Ek T, Mahachai V, Yamaoka Y. Prevalence, risk factors, and virulence genes of Helicobacter pylori among dyspeptic patients in two different gastric cancer risk regions of Thailand. PLoS One. 2017 Oct 30;12(10):e0187113. doi: 10.1371/journal.pone.0187113. PMID: 29084246
13.Subsomwong P, Miftahussurur M, Vilaichone RK, Ratanachu-Ek T, Suzuki R, Akada J, Uchida T, Mahachai V, Yamaoka Y. Helicobacter pylori virulence genes of minor ethnic groups in North Thailand. Gut Pathog. 2017 Oct 11;9:56. doi: 10.1186/s13099-017-0205-x. PMID: 29046726
Grants, Awards and Recognition
| 2022-2025 | Research Grant from Grant-in-Aid for Early-Career Scientist, Japan Society for the Promotion of Science (JSPS), Japan |
| 2021-2025 | Research Grant from Research Center for Global and Local Infectious Diseases (RCGLID), Oita University, Japan |
| 2018-2020 | Postdoctoral fellowship scholarship and Research Grant from Tokyo Biochemical Research Foundation (TBRF), Japan |
| 2013-2018 | Ph.D. scholarship from the Japanese Government (Monbukagakusho: MEXT) |