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ภาควิชาจุลชีววิทยา คณะวิทยาศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย
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Academic Staff

Wanchai Assavalapsakul, Professor, Ph.D.

Wanchai Assavalapsakul, Professor, Ph.D.

Education

2008 M.Sc. (Technology Management), Thammasat University
2004 Ph.D. (Molecular Genetics and Genetic Engineereing), Mahidol University
1998 B.Sc. (Genetics), Chulalongkorn University

Training

2004 Training in yeast two hybrid system at Queensland Bioscience Precinct, CSIRO, Brisbane , Australia
2008 Studying in miRNAs of Bovine Herpesvirus 1 at Queensland Agricultural Biotechnology Centre, University of Queensland, Brisbane, Australia
Networks
  • Collaboration with Prof. Emeritus Sakol Panyim in “Development of siRNA-based protective immunity for virus-infected shrimp” at Institute of Molecular Biosciences, Mahidol University
  • Collaboration with Prof. Duncan R Smith in “Host-Dengue Virus interation” at Institute of Molecular Biosciences, Mahidol University

Research Interest

– Virology and Molecular Biology
(i) Diagnostic and vaccine development for viral disease in livestock
(ii) Molecular approaches to fight shrimp viral diseases
(iii) Antiviral agents for dengue virus
(iv) Explore viral replication and host’s gene expression profiles upon viral infection
(v) Functional study of relevant genes; cloning, expression, purification and characterization from any interested viruses or hosts.

Research Profiles

2008-present Assistant Professor, Department of Microbiology, Faculty of Science, Chulalongkorn University
2008 Endeavour Research Fellowship, Australian Government
2005-2008 Lecturer, Department of Microbiology, Faculty of Science, Chulalongkorn University
2006 TRF-CHE Outstanding New Researcher Award, Thailand Research Fund and
Office of the Higher Education Commission
2005 Researcher, Institute of Molecular Biosciences, Mahidol University

Publications

From Research gate Click
From Scopus Click
From Orcid Click

Selected Publications

  1. Kaewpiboon C, Srisuttee R, Malilas W, Moon J, Oh S, Jeong HG, Johnston RN, Assavalapsakul W, Chung YH. Up-regulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance (MDR) 1 expression in human A549 lung cancer cells. Molecular Medicine Reports. (Accepted) (Impact factor 2012 : 1.170)
  2. Kaewpiboon C, Surapinit S, Malilas W, Moon J, Phuwapraisirisan P, Tip-Pyang S, Johnston RN, Koh SS, Assavalapsakul W, Chung,YH. Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells. Int J Oncol. 2014 : 44 (4) : 1233-1242. (Impact factor 2012 : 2.657)
  3. Kaewpiboon C, Srisuttee R, Malilas W, Moon J, Kaowinn S, Cho IR, Johnston RN, Assavalapsakul W, Chung YH.  Extract of Bryophyllum laetivirens etoposide resistance in human lung A549 cancer cells by downregulation of NF-κB. Oncol Rep. 2014 : 31 (1) : 161-168. (Impact factor 2012 : 2.297)
  4. Kaewpiboon C, Lirdprapamongkol K, Srisomsap C, Winayanuwattikun P, Yongvanich T, Phuwaprisirisan P, Svasti J, Assavalapsakul W. Studies of the in vitro antitumor, antioxidant, anti-obesity and antimicrobial activities of selected Thai medicinal plants. BMC Complem Altern Med, 12:217. doi: 10.1186/1472-6882-12-217. (Impact factor 2011 : 2.241)
  5. Glazov EA, Horwood PF, Assavalapsakul W, Kongsuwan K, Mitchell RW, Mitter N, Mahony TJ. Characterization of microRNAs encoded by the Bovine herpesvirus 1 genome. J. Gen Virol. 2010 ; 91 (1) : 32-41. (Impact Factor 2008 : 3.092)
  6. Glazov EA, Kongsuwan K, Assavalapsakul W, Horwood PF, Mitter N, Mahony TJ. Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection. PLoS One. 2009 ; 4 (7) : e6349. doi:10.1371/journal.pone.0006349. (Impact Factor 2009 : 4.351)
  7. Assavalapsakul W, Chinnirunwong W, Panyim S. Application of YHV-protease dsRNA for protection and therapeutic treatment against Yellow Head virus infection in Litopenaeus vannamei. Dis Aquat Organ. 2009 ; 84 (2) : 167-171. (Impact Factor 2008 : 1.598).
  8. Assavalapsakul W. Important shrimp viruses in Thai shrimp-farming industry : Yellow Head Virus, White Spot Syndrome Virus, and Taura Syndrome Virus. J Sci Res Chula Univ (Section T) 2007 ; 6 (1) : 1-8.
  9. Assavalapsakul W, Smith DR, Panyim S. Identification and characterization of a Penaeus monodon  lymphoid cell-expressed receptor for the yellow head virus. J. Virol. 2006 ; 80 (1) : 262-269. (Impact Factor 2006 : 5.178)
  10. Assavalapsakul W, Tirasophon W, Panyim S. Antiserum to the Gp116 glycoprotein of yellow head virus neutralizes infectivity in primary lymphoid organ cells of Penaeus monodon. Dis Aquat Organ. 2005 ; 63 (1) : 85-88. (Impact Factor 2005 : 1.361)
  11. Assavalapsakul W, Smith DR, Panyim S. Propagation of infectious yellow head virus particles prior to cytopathic effect in primary lymphoid cell cultures of Penaeus monodon. Dis Aquat Organ. 2003 ; 55 (3) : 253-258. (Impact Factor 2005 : 1.263)

Grants, Awards and Recognition

2010-2013 Discovery based Development Grant (DD Grant), National Science and Technology Development Agency, THAILAND
2010-2011 Ratchadaphiseksomphot Endowment Fund, THAILAND
2008-2010 ทุนพัฒนาศักยภาพในการทำงานวิจัยของอาจารย์รุ่นใหม่, สกว.-สกอ
2008  Endeavour Research Fellowship, Australian Government, AUSTRALIA 2006 Ratchadaphiseksomphot Endowment Fund, THAILAND
2005-2007 ทุนพัฒนาศักยภาพในการทำงานวิจัยของอาจารย์รุ่นใหม่, สกว.-สกอ
1999-2004 Royal Golden Jubilee Scholarship, Thailand Research Fund , THAILAND