Naraporn Somboonna, Associate Professor, Ph.D.

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Phone : 662 218 5095
Education
Present            Associate Professor, Faculty of Science, Chulalongkorn University, THAILAND
2008-2010       Researcher, National Center for Genetic Engineering and Biotechnology (BIOTEC), NSTDA, THAILAND
2008                Ph.D. in Bioengineering, University of California, Berkeley, and University of California, San Francisco, USA
2007-2008      Ph.D. Founder Region Award, Soroptimist International of the Americas
2005                M.Sc. in Infectious Diseases and Immunity, University of California, Berkeley, USA
2001                B.Sc. in Bacteriology (Honors, Biocore Honors Student), University of Wisconsin, Madison, USA
2001                B.Sc. in Molecular and Cell Biology, University of Wisconsin, Madison, USA
1999-2001       Biological Aide Position (Part-time), United States Department of Agriculture (USDA), Wisconsin, USA
 
Training
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Research Interest
Microbiome, Health, Unculturable microbes, Point-of-care diagnostics, Genomics
 
Publications from scopus

 
 
Other Publications
International (before 2010)
  1. Somboonna N*, Wilantho A, Rerngsamran P, Tongsima S, Chavanich S. Marine bacterial diversity in coastal Sichang island, the upper Gulf of Thailand, in 2011 wet season. Front Mar Sci 2019. doi: 10.3389/fmars.2019.00308 (Tier 1)
  2. Wongpiyabovorn J*, Soonthornchai W, Wilantho A, Palasuk M, Payungporn S, Sodsai P, Poomipak W, Weschawalit S, Ruchusatsawat K, Baillie GS, Hirankarn N, Somboonna N. Effect of tarcolimus on skin microbiome in atopic dermatitis. Allergy 2019. doi: 10.1111/all.13743 (Q1)
  3. Panpatch W, Somboonna N, Palasuk M, Heangrach P, Finkelman M, Tumwasorn S, Leelahavanichkul A*. Oral Candida administration in a Clostridium difficile mouse model worsens disease severity but is attenuated by Bifidobacterium. PLoS One 2019; 14(1): e0210798. doi: 10.1371/journal.pone.0210798 (Q1)
  4. Hiengrach P, Panpetch W, Worasilchai N, Chindamporn A, Tumwasorn S, Jaroonwitchawan T, Somboonna N, Wilantho A, Chathanathon P, Leelahavanichkul A*. Administration of Candida albicans to dextran sulfate solution treated mice causes intestinal dysbiosis, emergence and dissemination of intestinal Pseudomonas aeruginosa and lethal sepsis. Shock 2019. doi: 10.1097/SHK.0000000000001339 (Tier 1)
  5. Somboonna N, Ziklo N, Ferrin T, Suh J, Dean D*. Clinical persistence of Chlamydia trachomatis sexually transmitted strains involves novel mutations in the functional abba tetramer of the tryptophan synthase operon. mBio 2019; 10(4): e01464-19. (Tier 1)
  6. Somboonna N*, Choopara I. Point-of-care Chlamydia trachomatis detection using loop-mediated isothermal amplification and hydroxynaphthol blue. Methods Mol Biol 2019; 2042: 11-17. Doi: 10.1007/978-1-4939-9694-0_2 (Tier 2 – Springer Nature publisher)
  7. Panpetch W, Heangrach P, Chathanathon P, Wilantho A, Somboonna N* (co-correspondence), Leelahavanichkul A*. Additional Candida albicans administration enhances the severity of dextran sulfate solution induced colitis mouse model through leaky gut-enhanced systemic inflammation and gut-dysbiosis but attenuated by Lactobacillus rhamnosus L34. Gut Microbes 2019. Accepted. (Tier 1)
  8. Thim-uam A, Surawut S, Issara-Amphorn J, Jaroonwitchawan T, Hiengrach P, Chathanathon P, Wilantho A, Somboonna N, Palaga T, Pisitkun P, Leelahavanichkul A*. Leaky-gut enhanced lupus progression in lupus mouse models (Fc gamma receptor IIb deficiency and pristane), role of gut leakage induced systemic inflammation. Sci Rep 2019. Revised. (Tier 1)
  9. Somboonna N*, Choopara I, Arunrut N, Sukhonpan K, Sayasathid S, Dean D, Kiatpathomchai W. Rapid and sensitive detection of Chlamydia trachomatis sexually transmitted infections in resource-constrained settings in Thailand at the point-of-care. PLoS Negl Trop Dis 2018; 12(12): e0006900. (Tier 1)
  10. Bulan DE, Wilantho A, Krainara P, Viyakarn V, Chavanich S*, Somboonna N*. Spatial and seasonal variability of reef bacterial communities in the upper Gulf of Thailand. Front Mar Sci 2018; 5: 441. doi:10.3389/fmars.2018.00441 (Tier 1)
  11. Bulan DE, Wilantho A, Tongsima S, Viyakarn V, Chavanich S*, Somboonna N*. Microbial and small eukaryotes associated with reefs in the upper Gulf of Thailand. Front Mar Sci 2018; 5: 436. doi:10.3389/fmars.2018.00436 (Tier 1)
  12. Leelahavanichkul A*, Panpatch W, Somboonna N, Bulan DW, Issara-Amphorn J, Worasilchai N, Finkelman M, Chindamporn A, Palaga T, Tumwasorn S. Gastrointestinal colonization of Candida albicans increases serum (13)-ß-D-glucan, without candidemia and worsens cecal ligation and puncture sepsis in murine model. Shock 2018; 49(1): 62-70. doi: 10.1097/SHK.0000000000000896 (Tier 1)
  13. Somboonna N*, Wilantho A, Monanunsap S, Chavanich S, Tangphatsornruang S, Tongsima S. Microbial communities in the reef water at Kham Island, lower Gulf of Thailand. PeerJ 2017; 5: e3625. doi: 10.7717/peerj.3625 (Q1)
  14. Wilantho A, Deekaew P, Srisuttiyakorn C, Tongsima S, Somboonna N*. Diversity of bacterial communities on the facial skin of different age-group Thai males. PeerJ 2017; 5: e4084. doi: 10.7717/peerj.4084 (Q1)
  15. Somboonna N*, Wilantho A, Srisuttiyakorn C, Assawamakin A, Tongsima S. Bacterial communities on facial skin of teenage and elderly Thai females. Arch Microbiol 2017; 199: 1035-1042. (Q2)
  16. Panpetch W, Somboonna N (co-first author), Bulan DE, Issara-Amphorn J, Finfelman M, Worasilchai N, Chindamporn A, Palaga T, Tumwasorn S*, Leelahavanichkul A*. Oral administration of live- or heat-killed Candida albicans worsened cecal ligation and puncture sepsis in a murine model possible due to an increased serum (1®3)-ß-D-glucan. PLoS One 2017; 12: e0181439. doi: 10.1371/journal.pone.0181439 (Q1)
  17. Choopara I, Arunrut N, Kiatpathomchai W, Dean D, Somboonna N*. Rapid and visual Chlamydia trachomatis detection using loop-mediated isothermal amplification and hydroxynaphthol blue. Lett Appl Microbiol 2017; 64(1): 51-56. (Q2)
  18. Khitmoh K, Wilantho A, Wongsawaeng D, Tongsima S, Somboonna N*. 16S rRNA gene sequencing assessment of the prokaryotic communities in the southeast Andaman Sea, Thailand and potential environmental alerts. Chiang Mai J Sci 2017; 44(1): 15-28. (Q3)
  19. Wongsawaeng D*, Khemngern S, Somboonna N. Environmentally-friendly RF plasma treatment of Thai silk fabrics with chitosan for durable antibacterial property. Eng J 2017; 21(1): 29-43. (Q2)
  20. Somboonna N*, Choopara I, Sukhonpan K, Sayasathid J. Sexually transmitted diseases in symptomatic and asymptomatic Thai females (a study from Bangkok and vicinity). Asian Biomed 2015; 9(3): 299-311. (Q4)
  21. Somboonna N*, Assawamakin A, Wilantho A, Monanunsap S, Tangphatsornruang S, Tongsima S. Structural and functional diversity of free-living microorganisms in reef surface, Kra island, Thailand. BMC Genomics 2014; 15(607). doi:10.1186/1471-2164-15-607 (Tier 1)
  22. Somboonna N*, Wilantho A, Jankaew K, Assawamakin A, Sangsrakru D, Tangphatsornruang S, Tongsima S. Microbial ecology of Thailand tsunami and non-tsunami affected terrestrials. PLoS ONE 2014; 9(4): e94236. (Q1)
  23. Somboonna N*, Assawamakin A, Wilantho A, Tangphatsornruang S, Tongsima S. Metagenomic profiles of free-living archaea, bacteria and small eukaryotes in coastal areas of Sichang island, Thailand. BMC Genomics 2012; 13(Suppl7): S29. (Tier 1)
  24. Somboonna N. 2012. Different species of crabs and viral susceptibility. In N. Gotsiridze-Columbus (ed.), Crabs: anatomy, habitat and ecological significance. NOVA Science Publishers, Inc., Hauppauge, New York, USA; pp. 1-25.
  25. Somboonna N, Wan R, Ojcius DM, Pettengill MA, Joseph SJ, Chang A, Hsu R, Read TD, Dean D*. Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L2) and D lineages. mBio 2011; 2(3): e00045-11. doi:10.1128/mBio.00045-11. (Tier 1)
  26. Sayasathid J*, Somboonna N, Thapmaogkol S, Buddharadsa Y, Sukonpan K. Mediastinal teratoma in a neonate with acute respiratory failure. Asian Biomed 2011; 5(1): 123-127. (Q4)
  27. Sayasathid J, Sukonpan K, Somboonna N. 2011. Epidemiology and etiology of congenital heart diseases. In D. Danijela (ed.), Congenital heart disease. InTech – Open Access Publisher, Rijeka, Croatia.
  28. Somboonna N*, Mangkalanan S, Krittanai C, Sritunyalucksana K, Flegel TW. Mud crab susceptibility to disease from white spot syndrome virus is species-dependent. BMC Res Notes 2010; 3: 315. (Q2)
  29. Sayasathid J*, Supachokchaipattana P, Pipatvech K, Sukonpan K, Somboonna N, Pannarunothai S. The prevalence of unrecognized congenital heart disease among the elementary school students in lower northern Thailand. Asian Biomed. 2010; 4(1): 171-175. (Q4)
  30. Somboonna N, Dean D. Limited genomes and gene transfer in the evolution of intracellular parasitism and symbiosis. In U.E. Schaible, and A. Haas (eds.), Intracellular niches of pathogens – a microbe’s guide through the host cell. Wiley-VCH Press, Weinheim, Germany. 2009; pp. 21-32.
  31. Sayasathid J*, Tantiwongkosri K, Somboonna N. Unrecognized congenital heart disease among Thai children. J Med Assoc Thai. 2009; 92(3): 356-359. (Q3)
  32. Somboonna N, Mead S, Liu J, Dean D*. Discovering and dfferentiating new and emerging clonal populations of Chlamydia trachomatis with a novel shotgun cell culture harvest assay. Emerging Infect Dis 2008; 14(3): 445-453. (Tier 1)
  33. Sayasathid J*, Somboonna N, Numchaisiri J. Case report paraplegia after thoracotomy for division and suture Patent Ductus Arteriosus (PDA). J Med Assoc Thai 2006; 89 (12): 2142-2144. (Q3)
  34. Diep BA, Sensabaugh GF, Somboonna N, Carleton HA, Perdreau-Remington F. Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidin. J Clin Microbiol 2004; 42(5): 2080-2084. (Tier 1)
National
  1. Somboonna N, Sukhonpan K, Sayasathid J. Persistence of Chlamydia trachomatis sexually transmitted diseases การติดเชื้อแบบแอบแฝงของคลามัยเดียที่ก่อโรคติดต่อทางเพศสัมพันธ์. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2010; 27(3): 519-524. (impact factor = 0.092)
  2. Somboonna N, Charuchinda P. Effect of tryptophan synthase gene polymorphisms on different Chlamydia trachomatis infection patterns ความหลากหลายของกลุ่มยีนที่ทําหน้าที่เกี่ยวข้องกับการสังเคราะห์กรดอะมิโนทริปโทเฟนมีผลต่อรูปแบบการติดเชื้อที่ต่างกันของคลามัยเดีย. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2010; 28(3): 287-295. (impact factor = 0.092)
  3. Somboonna N. Persistence of Chlamydia trachomatis after antibiotic treatment in sexually transmitted disease females การคงอยู่แบบแอบแฝงชองเชื้อคลามัยเดียหลังรักษาด้วยยาปฏิชีวนะในหญิงที่ติดเชื้อทางเพศสัมพันธ์. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2012; 29(1): 108-113. (impact factor = 0.092)
  4. Choopara I, Somboonna N*. Current cervical cancer vaccine and its development strategy วัคซีนป้องกันมะเร็งปากมดลูกในปัจจุบันและแนวทางการพัฒนา. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2015; 32(1): 74-80. (impact factor = 0.092)
  5. Somboonna N*, Chitboonthavisuk C. Survival mechanisms of intracellular Staphylococcus aureus inside human cell กลไกการอยู่รอดของ Staphylococcus aureus ภายในเซลล์มนุษย์. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2015; 32(1): 65-73. (impact factor = 0.092)
  6. Wongjaikham W, Wongsawaeng D*, Somboonna N. Environmentally-friendly RF plasma treatment of Thai silk fabrics with chitosan for durable antibacterial property. KMUTNB Int J Appl Technol 2016; 9(2): 91-98.
  7. Somboonna N*, Wilantho A, Chanabun R, Khomkrachang P, Panha S. Soil microbiome in the Upper Northeast of Thailand. Unisearch J 2017; 4(1): 10-16.
  8. Somboonna N*, Chitboonthavisuk C. Life cycle of Burkholderia pseudomallei วงจรชีวิตของ Burkholderia pseudomallei. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2017; 34(1): 115-120. (impact factor = 0.092)
  9. Somboonna N*, Sukwattananipaat P, Junpra-ob S. Treatment vaccine for human papillomavirus infection วัคซีนเพื่อการรักษาโรคไวรัสก่อมะเร็งปากมดลูก. Buddhachinaraj Medical J พุทธชินราชเวชสาร 2019; Revised.
 
Grants, Awards and Recognition
2015
Faculty of Science Award for the Distinguished Young Scientist, Chulalongkorn University
2015-2016
Internal Research Fund from Asia Research Center, THAILAND 
2014-2016
Ratchadaphiseksomphot Endowment Fund, Chulalongkorn University, THAILAND
2014-2015
The Asahi Glass Foundation, THAILAND
2011-2012
Thailand Research Fund, THAILAND
2011-2012
New Researcher Scholarship, CSTS-MOST, THAILAND
2011-2012
Internal Research Fund from Asia Research Center, Chulalongkorn University, THAILAND
2011-2012
CU-LMU-AORI Fund, Chulalongkorn University, THAILAND
2011-2012 
A1B1 Fund, Chulalongkorn University, THAILAND
2010-2011 
Ratchadaphiseksomphot Endowment Fund for New Faculty, THAILAND
2008-2010 
NSTDA Professional Research Group Grant (Co-investigator), THAILAND
2009          
First-place B.Sc. Student Poster Presentation Award, Naresuan University, THAILAND 2007-2009 
Biomedical Engineering Society, USA
2007-2008 
Founder Region Fellowship, Soroptimist International of the Americas, USA 2007-2008  Public Health Service Grant (Co-investigator), National Institutes of Health (NIH), USA 
2008          
Co-host for BIOTEC Program in Science and Technology Festival, THAILAND
2007          
Ballet Performance in Fall Dance Showcase, University of California, Berkeley, USA
2007         
Conference Travel Grant, University of California, Berkeley, USA
2006          
Pin Award from Thai Cultural Ministry Representative, USA
2005          
Head Organizer for International Festival, University of California, Berkeley, USA
2005          
Head Organizer for Land Donation to Berkeley Thai Temple, USA
2001          
B.Sc. in Bacteriology (Biocore Honors Student, UW Honors Student), University of Wisconsin, Madison, USA
1998-2001 
Biology Honors Program (Biocore) Student, University of Wisconsin, Madison, USA
1998-2001 
Letter & Sciences Honors Society, University of Wisconsin, Madison, USA
1996          
First-role Honors Certificate & Honors Shield, Chulalongkorn University Demonstration School, THAILAND
1996          
B.Sc.-Ph.D. Thai Government Scholarship from Ministry of Sciences and Technology, THAILAND
1995-1985 
Second-Role Honors Certificates, Chulalongkorn University Demonstration School, THAILAND

 

Patents

  1. Detection methods for bacterial contamination in food and drink using genetic amplification techniques combined with double-stranded-DNA specific dye (no.1901005841)
 
Petty Patensts
  1. Detection methods for Chlamydia trachomatis bacteria causing sexually transmitted diseases in humans by colorimetric LAMP (petty patent # 1503002132)
  2. Detection methods for Chlamydia trachomatis bacteria causing sexually transmitted diseases in humans by LAMP with colorimetric nanogold probe (petty patent # 1503002153)
  3. Detection methods for food-poisoning Staphylococcus aureus enterotoxin A gene by colorimetric LAMP (no.16030012152)
  4. Detection methods for food-poisoning Staphylococcus aureus enterotoxin A gene by loop-mediated isothermal amplification combined with colorimetric nanogold probe (no.16030012151)
  5. Semi-quantitative detection methods for food-poisoning Staphylococcus aureus enterotoxin A gene by loop-mediated isothermal amplification combined with fluorescent dye (no.1703000138)
  6. Detection methods for Chlamydia trachomatis causing sexually transmitted diseases and human internal control by multiplex loop-mediated isothermal amplification (no.1803000456)
  7. Detection methods for cow in lactose-intolerant milk and drink products by single-step loop-mediated isothermal amplification (no.1803000457)
  8. Detection methods for total bacteria using color loop-mediated isothermal amplification (no.1803000458)
  9. Detection methods for pork gene in halal food by colorimetric loop-mediated isothermal amplification (no.1803002276)
  10. Detection methods for total fungi using color loop-mediated isothermal amplification (no. 1803002277)
  11. Water soluble fluorescent dye for DNA detection (no. 1801003409)
  12. Quantitative detection methods for total bacteria using color loop mediated isothermal amplification combined most probable number technique (no. 1903001090)
  13. Biological face mask innovation with 100% natural ingredients, chemical free, edible and degradable (no.1903002420)